Cine imaging in combination with delayed-enhancement MR allows identification of:
- Myocardial stunning following acute myocardial infarction
Stunning is defined as post ischemic myocardial dysfunction that persists despite restoration of normal blood flow.
Over time there can be a gradual return of contractile function depending on the trans murality of the ischemia.
If the degree of trans murality as seen on the delayed enhancement images is less than 50%, the myocardial function is likely to recover.
Over time there can be a gradual return of contractile function depending on the trans murality of the ischemia.
If the degree of trans murality as seen on the delayed enhancement images is less than 50%, the myocardial function is likely to recover.
- Hibernating myocardium in the setting of chronic ischemic heart disease.
Hibernation is a state in which some segments of the myocardium exhibit abnormalities of contractile function at rest.
This phenomenon is highly significant clinically because it usually manifests itself in the setting of chronic ischemia, that is potentially reversible by revascularization. The reduced coronary blood flow causes the myocytes to enter a low-energy 'sleep mode' to conserve energy.
There is an inverse relationship between the transmural extent of hyperenhancement, and the likelihood of wall motion recovery following revascularization.
If the transmural extent of late enhancement is less than 50% the function is likely to improve after revascularization.
This phenomenon is highly significant clinically because it usually manifests itself in the setting of chronic ischemia, that is potentially reversible by revascularization. The reduced coronary blood flow causes the myocytes to enter a low-energy 'sleep mode' to conserve energy.
There is an inverse relationship between the transmural extent of hyperenhancement, and the likelihood of wall motion recovery following revascularization.
If the transmural extent of late enhancement is less than 50% the function is likely to improve after revascularization.
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