Saturday, December 31, 2011

No reflow phenomenon

No reflow phenomenon is the failure of blood to reperfuse an ischemic area after the physical obstruction has been removed or bypassed.
No reflow zones are identified on late-enhancement images as a dark core surrounded by an enhancing rim.
This finding indicates the presence of damaged microvasculature in the core of an area of infarction
The presence of a 'no reflow' zone is associated with worse functional outcome, larger infarcts and adverse clinical outcome [8,9].
Both acute and chronic infarctions demonstrate delayed-enhancement, but an acute infarction can often be distinguished by the presence of a 'no reflow' zone and high signal on T2 weighted images. 

Left: no-reflow phenomenon
Right: four months later there is transmural enhancement indicating a transmural infarction

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