Ischemic versus non-ischemic
The causes of cardiomyopathy (CM) can be divided into ischemic and non-ischemic (1-5).
Ischemic CM
is defined as dysfunction of the left ventricle as a result of a chronic lack of oxygen due to coronary artery disease.
Delayed enhancement MR images will show fibrosis, which appears as high signal intensity in an area of coronary artery distribution.
Since all infarctions start subendocardially and may progress to transmural, the subendocardial region is always involved.
is defined as dysfunction of the left ventricle as a result of a chronic lack of oxygen due to coronary artery disease.
Delayed enhancement MR images will show fibrosis, which appears as high signal intensity in an area of coronary artery distribution.
Since all infarctions start subendocardially and may progress to transmural, the subendocardial region is always involved.
Non-ischemic CM
has a variable etiology, i.e. genetic, toxic, metabolic, infectious and idiopathic.
In nonischemic myocardial disease the delayed enhancement usually does not occur in a coronary artery distribution and is often midwall or epicardial rather than subendocardial or transmural.
has a variable etiology, i.e. genetic, toxic, metabolic, infectious and idiopathic.
In nonischemic myocardial disease the delayed enhancement usually does not occur in a coronary artery distribution and is often midwall or epicardial rather than subendocardial or transmural.
LEFT: Long axis late enhancement image in a patient with an inferior wall infarction with subendocardial enhancement in the territory of the right coronary artery RIGHT: 4-chamber late enhancement image in a patient with idiopathic dilated cardiomyopathy with midmyocardial enhancement |
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