Saturday, January 21, 2012

Diagnostic plan

LE was judged to be of ischemic origin in patients with a history of MI (suspicion of acute MI, known chronic MI, and signs of MI in ECG, echocardiography, or nuclear imaging analyses) and/or proven CAD in coronary catheter angiography (at least one coronary artery stenosis of ≥ 70%). 

In patients with angiographically excluded CAD and no history of MI, LE was suggested to be caused by nonischemic disease.

A comparison between hyperintense areas in T2-weighted TSE images and the LE was performed according to the above-described criteria.

All entities of non–infarction-related causes for LE were assessed, and the different patterns of LE were related to the underlying pathology, as confirmed by a final diagnosis based on clinical features, ECG (all patients), diagnostic imaging (echocardiography, 644 patients; unenhanced MRI, seven patients; nuclear imaging, 35 patients), and biopsy (six patients). 

LE=Late enhancement.
MI=Myocardial infarction.
CAD=Coronary artery disease.

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